Nobel Prize In Medicine Awarded To 'Body Clock' Scientists

Nobel Prize In Medicine Awarded To 'Body Clock' Scientists

This isn't the first time the three have been recognised for their work on circadian rhythms, however: in 2013, they shared the Shaw Prize in life science and medicine, then worth US$1 million. They experimented with fruit flies to find the gene that controls the daily biological rhythm.

We now know a lot more about the circadian rhythm, and subsequent scientists have expanded the research, finding similar proteins in humans (though there's still a lot of work to do).

Both Jeffrey C. Hall and Michael Rosbash worked at Brandeis University.

From left to right: Michael Young, Jeffrey Hall, and Michael Rosbash. In the 1980s, the pair collaborated with geneticist Michael W. Young, 68, of Rockefeller University in NY to characterize what are known as the "period" and "timeless" genes. Between them, studying mutated fruit flies, they put together an explanation of what is going on at a molecular level.

The awardees' work stems back to 1984, when Mr Rosbash and Mr Hall, who was then also at Brandeis, along with Mr Young isolated the "period gene" in fruit flies.

In 1994 Young discovered a second clock gene, which he named "timeless", that helps control the period gene's activity.

The statement further read, "We now recognize that biological clocks function by the same principles in cells of other multicellular organisms, including humans". He said he got the call about the award just after 5 a.m. (Benzer died in 2007.) At the time, the idea that behaviour could have a genetic basis was controversial, says Wijnen.

Lewis Hamilton expects Sebastian Vettel backlash in Malaysian Grand Prix
Lewis Hamilton and Valtteri Bottas struggled with grip and went off track into the gravel within moments of each other. Raikkonen turns 38 later this month, but the 2007 Formula One champion has been showing admirable form recently.

"The Swedish Academy has made a decision to announce the name of this year's Nobel Literature Prize laureate on Thursday, October 5, at 1:00 pm" (1100 GMT), the Academy wrote on its website on Monday.

Why it matters: Their combined work launched a subgenre of molecular biology that focused on circadian rhythm proteins.

The early 1980s was a much different time for DNA research-there was no human genome project, no CRISPR, and the computers used to evaluate DNA research were a lot slower.

Better understanding of the workings of the body clock has opened up a fascinating field of scientific quest. These rhythms show why disturbance in a particular pattern - such as lack of sleep due to jet lag or insomnia - could potentially have devastating consequences on the body and result in increased risk of many diseases.

The Nobel prize in Medicine previous year was won by Yoshinori Ohsumi, a Japanese cell biologist, for discovering the process called "autophagy" in which cells destroy and recycle cellular components. In 2002, he became associated with the University of Maine.

Research on the body clock has helped scientists improve health. "I hadn't even had a thought about this", he said.

Related News:

  • PH production PMI still subdued in September: IHS Markit

    PH production PMI still subdued in September: IHS Markit

    Malaysian manufacturers continued to raise their staffing levels despite the ongoing decline in new work. Longer lead times stemmed from a lack of raw materials among vendors, according to anecdotal evidence.
    Cueto struggles, but Sandoval's HR helps Giants top Padres

    Cueto struggles, but Sandoval's HR helps Giants top Padres

    He has a career record of 104-118 with a 3.69 ERA, and on June 13, 2012, Cain pitched a ideal game against the Houston Astros . The Giants lost 23 more games than they did last season in their worst year since 1985, when they lost 100 games.
    Congress terms rescheduling of Gandhi's visit to Amethi as 'murder of democracy'

    Congress terms rescheduling of Gandhi's visit to Amethi as 'murder of democracy'

    Uttar Pradesh Congress Committee chief Raj Babbar termed the attempt to postpone Rahul's visit by the district administration an act of "cowardice and fear".
  • Donald Trump to visit Asia in November, but India not in itinerary

    Donald Trump to visit Asia in November, but India not in itinerary

    The White House said that Trump will travel to China, Japan, South Korea, Vietnam and the Philippines. The US president will be accompanied by First Lady Melania Trump.
    'NOBODY is unsackable' Philip Hammond blasts Boris Johnson's leadership bid

    'NOBODY is unsackable' Philip Hammond blasts Boris Johnson's leadership bid

    Mrs May responded: "What I have is a cabinet that are united in the mission of this Government Andrew, and that's what you will see this week".
    Seahawks reportedly believe Chris Carson suffered broken ankle

    Seahawks reportedly believe Chris Carson suffered broken ankle

    He needed to be carted off and have his leg placed in an air cast after being stood up by defenders and driven backwards. Hilton posted 153 yards and a touchdown in seven receptions while Dontre Moncrief added 44 yards in two catches.
  • Google scraps free content rule for publishers

    Google scraps free content rule for publishers

    News search results for sites with paid subscriptions will no longer be demoted in Google search , Bloomberg reported Sunday. Gingras says that they have been collaborating with news publishers to address such problems.
    Shiv Sena's strategy for BJP: Support but oppose too

    Shiv Sena's strategy for BJP: Support but oppose too

    Asked if he aspires to become the Chief Minister, he said, "I still have an ambition to become the Chief Minister of Maharashtra. Mr Fadnavis opposed his induction to avoid that embarrassment", said close confidant of the chief minister. "It never dies.
    Evidence Shows 2 Foreign Women Killed Jong-Nam By Poisoning Him - Prosecution

    Evidence Shows 2 Foreign Women Killed Jong-Nam By Poisoning Him - Prosecution

    Defence lawyers are convinced the real culprits have left Malaysia and that the women's innocence will be proven in court. The lawyers allege that the prosecutor did not convey significant parts of the record and criticize the investigation.
  • Playstation unveils updated VR headset

    Playstation unveils updated VR headset

    To check the event, it will dispatch a progression of recordings praising the gadget and the prevalent accomplishments. In Japan, the updated VR headset (in a bundle with the PlayStation Camera) will cost ¥44,980 (about $400).

    Trump accuses San Juan mayor of 'poor leadership'

    Trump said the US territory, which already was facing mounting debt and a shrinking economy, will need a costly recovery effort. According to the administration, more than 90 percent of the island now is now accessible; some 200 gas stations are open.
    Trump cites 'great job' in helping Puerto Rico

    Trump cites 'great job' in helping Puerto Rico

    The President also accused the news media of doing all it could to skew the story of the Puerto Rico relief effort, as Mr. Trump temporarily waived the Jones Act earlier this week to ease the delivery of aid by sea to Puerto Rico .


Most liked

Hurricane islanders want us to do everything for them, claims Donald Trump
As of Thursday, most of Puerto Rico remains at a standstill after Hurricane Maria slammed into it almost two weeks ago. Trump accused Cruz of being egged into her biting criticisms by Democrats who told her she "must be nasty to Trump".

NAS Meridian training jet may have crashed in Tennessee
Monroe County Sheriff's Office confirms they are responding to reports of a plane crash Sunday afternoon in Tellico Plains. A Navy official told Fox News that a T-45 jet was missing after taking off from MS earlier Sunday.

Donald Trump Dedicates A Golf Trophy To Hurricane Victims
Her tone was far different Friday when she accused the Trump administration of "killing us with the inefficiency" after the storm. Fifty-nine hospitals are partially operational, and 45 percent of customers have access to drinking water, officials said.

McDonald's is releasing Szechuan sauce-for real
A joke about Szechuan sauce was included in Rick and Morty's season three premiere, which debuted on April Fool's Day and was available to watch online for 48 hours.

KRG to pay price over independence referendum: Erdogan
Now businesses near the Turkish border fear their crossing may also close. Baghdad declared the ballot illegal and suspended flights in retaliation.

J&K: Child killed, five civilians injured as Pakistan violates ceasefire in Poonch
He called Pakistan's firing an unprovoked violation of the 2003 cease-fire accord between the two nuclear-armed rivals. Pakistani troops once again broke the ceasefire terms along the LoC .

San Juan mayor pushes back on Trump admin
President Donald Trump says Washington is - in his words - "fully engaged in the disaster and the response and recovery effort". Trump also criticized Puerto Rican officials for waiting for federal help to begin responding to the storm. "I could've played.

Places to visit on Gandhi Jayanti!!
He said the state had targeted the construction of 22 lakh individual toilets as part of Swachch Bharat by March 31, 2018. Mohandas Karamchand Gandhi was born on October 2, 1869, in Gujarat's Porbandar town to Putlibai and Karamchand Gandhi.

Longtime Hockey Broadcaster Dave Strader Dies At 62
In April, the Hockey Hall of Fame presented Strader with the Foster Hewitt Memorial Award for his contributions as a broadcaster. That game, of course, featured the Red Wings and Blackhawks, so it was a thrill to hear The Voice here in Detroit again.

Herath spins Sri Lanka to victory as hosts collapse
Ali was dismissed after scoring 85 runs today, followed by skipper Sarfraz Ahmed on 18 and bowler Mohammad Amir on four runs. His dismissal of Mohammed Abbas, during a frenzied final session in Abu Dhabi , sent Pakistan to a 21-run loss.

Trump tells Tillerson he's wasting his time
The standoff has entered a new, more unsafe phase since then as Kim and Trump have exchanged personal insults and threats of war. America's top diplomat has acknowledged the U.S. is in "direct contact" with North Korea.

Palestinian PM in Gaza on 1st visit after decade of Hamas rule
The potential outcomes are numerous, including the very real possibility that the unity talks will once again fail. At the Erez (Beit Hanun) crossing, several government ministers and security personnel accompanied Hamdallah.

Dubai announces launch of massive Mars Science City project
The creation of Mars Science City is led by a team from the Mohammed bin Rashid Space Centre and Dubai Municipality . The Emirati government Tuesday announced its plan to build a scientific city exemplifying life on planet Mars .

Retired Army JCO Asked To Prove His Nationality By The Government
Earlier in 2012, Haque's wife Mumtaz Begum, was summoned by the same Foreigner's Tribunal and was asked to prove her citizenship. The police have registered a case against Hoque, alleging he had entered Assam illegally without any valid documents.

Rural presence of Airtel and Reliance Jio in June 2017
Bharti Airtel MD and CEO for India and South Asia Gopal Vittal too rued the high taxes in the industry. Idea Cellular, India's No. 3 telecom firm, reported a third straight quarterly loss in June quarter.