Nobel Prize In Medicine Awarded To 'Body Clock' Scientists

Nobel Prize In Medicine Awarded To 'Body Clock' Scientists

This isn't the first time the three have been recognised for their work on circadian rhythms, however: in 2013, they shared the Shaw Prize in life science and medicine, then worth US$1 million. They experimented with fruit flies to find the gene that controls the daily biological rhythm.

We now know a lot more about the circadian rhythm, and subsequent scientists have expanded the research, finding similar proteins in humans (though there's still a lot of work to do).

Both Jeffrey C. Hall and Michael Rosbash worked at Brandeis University.

From left to right: Michael Young, Jeffrey Hall, and Michael Rosbash. In the 1980s, the pair collaborated with geneticist Michael W. Young, 68, of Rockefeller University in NY to characterize what are known as the "period" and "timeless" genes. Between them, studying mutated fruit flies, they put together an explanation of what is going on at a molecular level.

The awardees' work stems back to 1984, when Mr Rosbash and Mr Hall, who was then also at Brandeis, along with Mr Young isolated the "period gene" in fruit flies.

In 1994 Young discovered a second clock gene, which he named "timeless", that helps control the period gene's activity.

The statement further read, "We now recognize that biological clocks function by the same principles in cells of other multicellular organisms, including humans". He said he got the call about the award just after 5 a.m. (Benzer died in 2007.) At the time, the idea that behaviour could have a genetic basis was controversial, says Wijnen.

"The Swedish Academy has made a decision to announce the name of this year's Nobel Literature Prize laureate on Thursday, October 5, at 1:00 pm" (1100 GMT), the Academy wrote on its website on Monday.

Why it matters: Their combined work launched a subgenre of molecular biology that focused on circadian rhythm proteins.

The early 1980s was a much different time for DNA research-there was no human genome project, no CRISPR, and the computers used to evaluate DNA research were a lot slower.

Better understanding of the workings of the body clock has opened up a fascinating field of scientific quest. These rhythms show why disturbance in a particular pattern - such as lack of sleep due to jet lag or insomnia - could potentially have devastating consequences on the body and result in increased risk of many diseases.

The Nobel prize in Medicine previous year was won by Yoshinori Ohsumi, a Japanese cell biologist, for discovering the process called "autophagy" in which cells destroy and recycle cellular components. In 2002, he became associated with the University of Maine.

Research on the body clock has helped scientists improve health. "I hadn't even had a thought about this", he said.

Related News:

  • Trump blasts media coverage of Puerto Rico

    Trump blasts media coverage of Puerto Rico

    That comes after he accused the San Juan mayor of poor leadership and being unable to get workers to help Puerto Rico recover. He also noted that he and the first lady will be traveling to Puerto Rico and possibly the U.S.
    Seahawks reportedly believe Chris Carson suffered broken ankle

    Seahawks reportedly believe Chris Carson suffered broken ankle

    He needed to be carted off and have his leg placed in an air cast after being stood up by defenders and driven backwards. Hilton posted 153 yards and a touchdown in seven receptions while Dontre Moncrief added 44 yards in two catches.
    Marlins' Don Mattingly may move Giancarlo Stanton to leadoff spot

    Marlins' Don Mattingly may move Giancarlo Stanton to leadoff spot

    Brewers 6, Cardinals 1: Aaron Wilkerson took a ideal game into the sixth inning and Brett Phillips hit a three-run homer. Marlins recap including top players, game statistics, a standings update, and what's next for both of these teams.
  • Cueto struggles, but Sandoval's HR helps Giants top Padres

    Cueto struggles, but Sandoval's HR helps Giants top Padres

    He has a career record of 104-118 with a 3.69 ERA, and on June 13, 2012, Cain pitched a ideal game against the Houston Astros . The Giants lost 23 more games than they did last season in their worst year since 1985, when they lost 100 games.
    Congress terms rescheduling of Gandhi's visit to Amethi as 'murder of democracy'

    Congress terms rescheduling of Gandhi's visit to Amethi as 'murder of democracy'

    Uttar Pradesh Congress Committee chief Raj Babbar termed the attempt to postpone Rahul's visit by the district administration an act of "cowardice and fear".
    Retired Army JCO Asked To Prove His Nationality By The Government

    Retired Army JCO Asked To Prove His Nationality By The Government

    Earlier in 2012, Haque's wife Mumtaz Begum, was summoned by the same Foreigner's Tribunal and was asked to prove her citizenship. The police have registered a case against Hoque, alleging he had entered Assam illegally without any valid documents.
  • Playstation unveils updated VR headset

    Playstation unveils updated VR headset

    To check the event, it will dispatch a progression of recordings praising the gadget and the prevalent accomplishments. In Japan, the updated VR headset (in a bundle with the PlayStation Camera) will cost ¥44,980 (about $400).
    Trump tells Tillerson he's wasting his time

    Trump tells Tillerson he's wasting his time

    The standoff has entered a new, more unsafe phase since then as Kim and Trump have exchanged personal insults and threats of war. America's top diplomat has acknowledged the U.S. is in "direct contact" with North Korea.
    Dubai announces launch of massive Mars Science City project

    Dubai announces launch of massive Mars Science City project

    The creation of Mars Science City is led by a team from the Mohammed bin Rashid Space Centre and Dubai Municipality . The Emirati government Tuesday announced its plan to build a scientific city exemplifying life on planet Mars .
  • Myanmar Repairs, Fortifies Fence on Bangladeshi Border

    Myanmar Repairs, Fortifies Fence on Bangladeshi Border

    Bangladeshi home minister will shortly visit Myanmar for discussion over the border management proposal, said Mahmood Ali. Ali told reporters that the counties had agreed to form a joint working group to start work on repatriation.
    NAS Meridian training jet may have crashed in Tennessee

    NAS Meridian training jet may have crashed in Tennessee

    Monroe County Sheriff's Office confirms they are responding to reports of a plane crash Sunday afternoon in Tellico Plains. A Navy official told Fox News that a T-45 jet was missing after taking off from MS earlier Sunday.

    Trump accuses San Juan mayor of 'poor leadership'

    Trump said the US territory, which already was facing mounting debt and a shrinking economy, will need a costly recovery effort. According to the administration, more than 90 percent of the island now is now accessible; some 200 gas stations are open.


Most liked

Hurricane islanders want us to do everything for them, claims Donald Trump
As of Thursday, most of Puerto Rico remains at a standstill after Hurricane Maria slammed into it almost two weeks ago. Trump accused Cruz of being egged into her biting criticisms by Democrats who told her she "must be nasty to Trump".

PH production PMI still subdued in September: IHS Markit
Malaysian manufacturers continued to raise their staffing levels despite the ongoing decline in new work. Longer lead times stemmed from a lack of raw materials among vendors, according to anecdotal evidence.

Donald Trump Dedicates A Golf Trophy To Hurricane Victims
Her tone was far different Friday when she accused the Trump administration of "killing us with the inefficiency" after the storm. Fifty-nine hospitals are partially operational, and 45 percent of customers have access to drinking water, officials said.

McDonald's is releasing Szechuan sauce-for real
A joke about Szechuan sauce was included in Rick and Morty's season three premiere, which debuted on April Fool's Day and was available to watch online for 48 hours.

KRG to pay price over independence referendum: Erdogan
Now businesses near the Turkish border fear their crossing may also close. Baghdad declared the ballot illegal and suspended flights in retaliation.

Heidi Montag & Spencer Pratt Welcome A Baby Boy - Inside Her Dramatic Delivery!
The new dad Pratt took his Twitter and tweeted, "Shout out @ crystalarium1 for dropping off $27,000 in crystals for the birth ". According to Us Weekly , baby boy Pratt was born at 3:06 p.m, weighing in at 6 pounds, 12 ounces, and measuring 19 inches long.

Shiv Sena's strategy for BJP: Support but oppose too
Asked if he aspires to become the Chief Minister, he said, "I still have an ambition to become the Chief Minister of Maharashtra. Mr Fadnavis opposed his induction to avoid that embarrassment", said close confidant of the chief minister. "It never dies.

San Juan mayor pushes back on Trump admin
President Donald Trump says Washington is - in his words - "fully engaged in the disaster and the response and recovery effort". Trump also criticized Puerto Rican officials for waiting for federal help to begin responding to the storm. "I could've played.

US 'Probing' Dialogue With North Korea, Tillerson Says
The Korean Peninsula stays in a specialized condition of war, and the Neutral territory separates North and South Korea. He then said the U.S. had "a couple of, three channels open to Pyongyang". "We're not in a dark situation, a blackout".

Longtime Hockey Broadcaster Dave Strader Dies At 62
In April, the Hockey Hall of Fame presented Strader with the Foster Hewitt Memorial Award for his contributions as a broadcaster. That game, of course, featured the Red Wings and Blackhawks, so it was a thrill to hear The Voice here in Detroit again.

Herath spins Sri Lanka to victory as hosts collapse
Ali was dismissed after scoring 85 runs today, followed by skipper Sarfraz Ahmed on 18 and bowler Mohammad Amir on four runs. His dismissal of Mohammed Abbas, during a frenzied final session in Abu Dhabi , sent Pakistan to a 21-run loss.

Evidence Shows 2 Foreign Women Killed Jong-Nam By Poisoning Him - Prosecution
Defence lawyers are convinced the real culprits have left Malaysia and that the women's innocence will be proven in court. The lawyers allege that the prosecutor did not convey significant parts of the record and criticize the investigation.

Trump cites 'great job' in helping Puerto Rico
The President also accused the news media of doing all it could to skew the story of the Puerto Rico relief effort, as Mr. Trump temporarily waived the Jones Act earlier this week to ease the delivery of aid by sea to Puerto Rico .

Nawaz Sharif's party set to elect him chief
Mohsin Shahnawaz Ranjha said that past of PML-N was spotless and it was facing the courts. But the vote was more of a formality as PML-N has a vast majority.

Bangladesh 49-3, facing big target of 424 vs. South Africa
Covers were brought on soon after as it began raining heavily but it wasn't the persistent kind that causes lengthy delays. Du Plessis dropped the chance to deny Kagiso Rabada an early wicket but it didn't cost South Africa too much.