Hair loss breakthrough: Osteoporosis drug fights male and female baldness

NewsScienceHas baldness finally been cured?Joe Mellor

Two drugs are now known to treat male-pattern baldness or androgenetic alopecia: minoxidil and finasteride.

Minoxidil and finasteride are now the only drugs prescribed to treat pattern baldness "but both have side effects and often produce disappointing results", says The Daily Telegraph.

In experiments, follicles provided by over 40 patients going through hair transplant surgery were given the osteoporosis drug for 6 Days. In the USA, there are around 50 million men and 30 million women affected by hair loss, which United Kingdom -based researchers said could be the source of "psychological distress". This target, which is the same mechanism as that of CsA, meant that when HFs were treated with WAY-316606 hair growth was enhanced.

It started with a hunt for novel agents to treat male pattern baldness, it marked down few candidates that were recognized to have hair growth as a outcome owing to their other damaging effects. They discovered it worked by reducing the activity of a protein - SFRP1 - that prevents the growth of hair follicles. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

But the only existing drugs to treat it are minoxidil and finasteride, which have previously been said by experts to work better at stalling hair loss than causing new hair to grow.

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There is a third option of a hair transplant, but this can be costly and out of reach for many men.

Ultimately, a permanent hair loss solution will be found in some form of stem cell treatment, Day believes: "When there's money to be made, there's research that's going to be done". Following 2 Days, the evaluated hair shaft production rate augmented considerably in the treated follicles.

However, Dr Hawkshaw said that further clinical trials will be needed to test the safety as well as effectiveness of the drug in people.

Hawkshaw said that a clinical trial is still necessary to make sure the drug is effective and safe to use for this propose.

However, it often has severe side-effects, the least serious - but most interesting - of which is that it enhances cosmetically unwanted hair growth.

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